Glimepiride sulfonamide

Glimepiride sulfonamide - Names and Identifiers

Name	4-[2-[(3-Ethyl-4-methyl-2-oxo-3-pyrroline)carboxamido]ethyl]benzene sulfonamide
Synonyms	Glimepiride sulfonamide Glimepiride Impurity 2(Glimepiride EP Impurity B) 4-[2-(3-Ethyl-4-Methyl-2-Oxo-3-Pyrroline-1-Carboxamide)Ethyl]Sulphonamide 4-[2-(3-Ethyl-4-methyl-2-oxo-3-pyrroline-1-carboxamidoethyl]benzenesulfonamide 4-(2-(3-ethyl-4-methyl-2-oxo-3-pyrroline-1-carboxamido)-ethyl)-Benzenesulfonyl 4-[2-[(3-Ethyl-4-methyl-2-oxo-3-pyrroline)carboxamido]ethyl]benzene sulfonamide 4-(2-(3-Ethyl-4-Methyl-2-Oxo-3-Pyrroline-1-Carboxamido)-Ethyl)-Benzenesulfonyl A 4-[2-(3-ethyl-4-methyl-2-oxo-3-pyrroline-1-carboxamido)ethyl]benezenesulfonamide N-[4-2-(3-Ethyl-4-Methyl-2-Oxo-3-Pyrroline-1-Carboxamido)-Ethyl]Benzensulfonamide 4-[2-[(3-Ethyl-4-methyl-2-oxo-3-pyrrolin-1-yl)carboxamido]ethyl]benzenesulfonamide N-[2-[4-(AMINOSULFONYL)PHENYL]ETHYL]-3-ETHYL-4-METHYL-2-OXO-1H-PYRROLE-1-CARBOXAMIDE 3-ethyl-4-methyl-2-oxo-N-[2-(4-sulfamoylphenyl)ethyl]-2,5-dihydro-1H-pyrrole-1-carboxamide n-[2-[4-(aminosulfonyl)phenyl]ethyl]-3-ethyl-2,5-dihydro-4-methyl-2-oxo-1h-pyrrole-1-carboxamide
CAS	119018-29-0
EINECS	411-850-0
InChI	InChI=1/C16H21N3O4S/c1-3-14-11(2)10-19(15(14)20)16(21)18-9-8-12-4-6-13(7-5-12)24(17,22)23/h4-7H,3,8-10H2,1-2H3,(H,18,21)(H2,17,22,23)
InChIKey	AJEMFZRCUKJSES-UHFFFAOYSA-N

Glimepiride sulfonamide - Physico-chemical Properties

Molecular Formula	C16H21N3O4S
Molar Mass	351.42
Density	1.304
Melting Point	177-179?C
Solubility	DMSO (Slightly), Methanol (Slightly, Sonicated)
Appearance	White solid
Color	White to Off-White
pKa	10.16±0.10(Predicted)
Storage Condition	Sealed in dry,Room Temperature
Refractive Index	1.588

Glimepiride sulfonamide - Risk and Safety

Risk Codes	52/53 - Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
Safety Description	61 - Avoid release to the environment. Refer to special instructions / safety data sheets.
HS Code	2935909550

Glimepiride sulfonamide - Introduction

4-[2-[(3-ethyl-4-methyl-2-oxo-3-pyrroline) carboxamido] ethyl] benzenesulfonamide is an organic compound, its properties, uses, preparation and safety information are as follows:

Nature:
-Appearance: Colorless to light yellow solid
-Molecular formula: C17H21N3O4S
-Molecular weight: 367.43g/mol
-Melting point: about 140-150°C
-Solubility: Good solubility in polar solvents

Use:
- 4-[2-[(3-ethyl-4-methyl-2-oxo-3-pyrroline) carboxamido] ethyl] benzenesulfonamide has fluorescent properties and is commonly used in the preparation of optical materials, fluorescent labeling agents and other fields.

Preparation Method:
The preparation of 4-[2-[(3-ethyl-4-methyl-2-oxo-3-pyrroline) carboxamido] ethyl] benzenesulfonamide can be carried out by the following steps:
1. Synthesis of 3-ethyl -4-methyl-2-oxo-3-pyrrole Lin (Lin).
2.3-ethyl -4-methyl -2-oxo -3-pyrrole Lin is reacted with glycidyl formate to generate methyl 2-carboxamide ethyl benzene sulfonate.
3. react methyl 2-carboxamidoethyl benzenesulfonate with ethylenediamine to generate 4-[2-[(3-ethyl -4-methyl -2-oxo -3-pyrrole Lin) carboxamido] ethyl] benzenesulfonamide.

Safety Information:
- 4-[2-[(3-ethyl-4-methyl-2-oxo-3-pyrrolinn) carboxamido] ethyl] benzenesulfonamide should be avoided with strong oxidants and strong acids Contact to avoid dangerous reactions.
-During the operation, care should be taken to prevent inhalation of its dust or solution and avoid contact with skin and eyes. If accidental contact, should immediately rinse with water.
-in storage, should be sealed in a cool, dry, well-ventilated place, away from the fire source and open flame.
-When using or handling the compound, observe appropriate safety procedures and wear appropriate personal protective equipment, such as respirators, protective glasses and protective clothing.

Last Update：2024-04-10 22:29:15